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1

T Cell Receptor V Genes in Multiple Sclerosis: Increased Use of TCRAV8 and TCRBV5 in MBP-Specific Clones

Offner, Halina, Vandenbark, Arthur A.

Journal:

International Reviews Of Immunology

Year:

1999

Language:

english

File:

PDF, 1.46 MB

english, 1999

2

The role of the spleen in ischemic stroke

Pennypacker, Keith R, Offner, Halina

Journal:

Journal of Cerebral Blood Flow and Metabolism

Year:

2015

Language:

english

File:

PDF, 99 KB

english, 2015

3

PD-L1 Monoclonal Antibody Treats Ischemic Stroke by Controlling Central Nervous System Inflammation

Bodhankar, Sheetal, Chen, Yingxin, Lapato, Andrew, Dotson, Abby L., Wang, Jianming, Vandenbark, Arthur A., Saugstad, Julie A., Offner, Halina

Journal:

Year:

2015

Language:

english

File:

PDF, 1.03 MB

english, 2015

4

Targeting immune co-stimulatory effects of PD-L1 and PD-L2 might represent an effective therapeutic strategy in stroke

Bodhankar, Sheetal, Chen, Yingxin, Lapato, Andrew, Vandenbark, Arthur A., Murphy, Stephanie J., Offner, Halina

Journal:

Frontiers in Cellular Neuroscience

Year:

2014

Language:

english

File:

PDF, 1.88 MB

english, 2014

5

Myelin basic crotein-specific and TCR Vβ8.2-Specific T-cell lines from TCR Vβ8.2 transgenic mice utilize the same Vα and Vβ genes: specificity associated with the Vα CDR3-Jα region

Abigail C. Buenafe, Rachel C. Tsu, Bruce Bebo, Jr., Arthur A. Vandenbark, Halina Offner

Journal:

Journal of Neuroscience Research

Year:

1997

Language:

english

File:

PDF, 194 KB

english, 1997

6

Similar pattern of MCP-1 expression in spinal cords and eyes of Lewis rats with experimental autoimmune encephalomyelitis associated anterior uveitis

Grazyna Adamus, Michal Machnicki, Drake Amundson, Kirsten Adlard, Halina Offner

Journal:

Journal of Neuroscience Research

Year:

1997

Language:

english

File:

PDF, 434 KB

english, 1997

7

Gender differences in experimental autoimmune encephalomyelitis develop during the induction of the immune response to encephalitogenic peptides

Bruce F. Bebo Jr., Jeanette C. Schuster, Arthur A. Vandenbark, Halina Offner

Journal:

Journal of Neuroscience Research

Year:

1998

Language:

english

File:

PDF, 73 KB

english, 1998

8

Neonatal exposure of TCR BV8S2 transgenic mice to recombinant TCR BV8S2 results in reduced T cell proliferation and elevated antibody response to BV8S2, and increased severity of EAE

Botond Siklodi, Raymond Jacobs, Arthur A. Vandenbark, Halina Offner

Journal:

Journal of Neuroscience Research

Year:

1998

Language:

english

File:

PDF, 84 KB

english, 1998

9

Gender differences in protection from EAE induced by oral tolerance with a peptide analogue of MBP-Ac1–11

Bruce F. Bebo Jr., Kirsten Adlard, Jeanette C. Schuster, Laura Unsicker, Arthur A. Vandenbark, Halina Offner

Journal:

Journal of Neuroscience Research

Year:

1999

Language:

english

File:

PDF, 184 KB

english, 1999

10

Ganglioside modulation of CD4 does not block T-helper cell function as compared to antagonism by anti-CD4 antibody

William J. Morrison, Halina Offner, Arthur A. Vandenbark

Journal:

Drug Development Research

Year:

1992

Language:

english

File:

PDF, 526 KB

english, 1992

11

Myelin oligodendrocyte glycoprotein-35–55 peptide induces severe chronic experimental autoimmune encephalomyelitis in HLA-DR2-transgenic mice

Cathleen Rich, Jason M. Link, Alex Zamora, Helle Jacobsen, Roberto Meza-Romero, Halina Offner, Richard Jones, Gregory G. Burrows, Lars Fugger, Arthur A. Vandenbark

Journal:

European Journal of Immunology

Year:

2004

Language:

english

File:

PDF, 301 KB

english, 2004

12

Estrogen-induced protection against experimental autoimmune encephalomyelitis is abrogated in the absence of B cells

Sheetal Bodhankar, Chunhe Wang, Arthur A. Vandenbark, Halina Offner

Journal:

European Journal of Immunology

Year:

2011

Language:

english

File:

PDF, 495 KB

english, 2011

13

TCR-like antibodies distinguish conformational and functional differences in two- versus four-domain auto reactive MHC class II–peptide complexes

Rony Dahan, Moran Tabul, Yuan K. Chou, Roberto Meza-Romero, Shayne Andrew, Adolph J. Ferro, Gregory G. Burrows, Halina Offner, Arthur A. Vandenbark, Yoram Reiter

Journal:

European Journal of Immunology

Year:

2011

Language:

english

File:

PDF, 485 KB

english, 2011

14

Effects of cytokine deficiency on chemokine expression in CNS of mice with EAE

Agata Matejuk, Jami Dwyer, Atsushi Ito, Zachary Bruender, Arthur A. Vandenbark, Halina Offner

Journal:

Journal of Neuroscience Research

Year:

2002

Language:

english

File:

PDF, 214 KB

english, 2002

15

Estrogen inhibition of EAE involves effects on dendritic cell function

Hong Yan Liu, Abigail C. Buenafe, Agata Matejuk, Atsushi Ito, Alex Zamora, Jami Dwyer, Arthur A. Vandenbark, Halina Offner

Journal:

Journal of Neuroscience Research

Year:

2002

Language:

english

File:

PDF, 1.09 MB

english, 2002

16

Endogenous CD4+BV8S2− T cells from TG BV8S2+ donors confer complete protection against spontaneous experimental encephalomyelitis (Sp-EAE) in TCR transgenic, RAG−/− mice

Agata Matejuk, Abigail C. Buenafe, Jami Dwyer, Atsushi Ito, Marc Silverman, Alex Zamora, Sandhya Subramanian, Arthur A. Vandenbark, Halina Offner

Journal:

Journal of Neuroscience Research

Year:

2003

Language:

english

File:

PDF, 372 KB

english, 2003

17

CNS gene expression pattern associated with spontaneous experimental autoimmune encephalomyelitis

Agata Matejuk, Corwyn Hopke, Jami Dwyer, Sandhya Subramanian, Richard E. Jones, Dennis N. Bourdette, Arthur A. Vandenbark, Halina Offner

Journal:

Journal of Neuroscience Research

Year:

2003

Language:

english

File:

PDF, 161 KB

english, 2003

18

Functional assay for human CD4+CD25+ Treg cells reveals an age-dependent loss of suppressive activity

Laura Tsaknaridis, Leslie Spencer, Nicole Culbertson, Kevin Hicks, Dorian LaTocha, Yuan K. Chou, Ruth H. Whitham, Antony Bakke, Richard E. Jones, Halina Offner, Dennis N. Bourdette, Arthur A. Vandenba

Journal:

Journal of Neuroscience Research

Year:

2003

Language:

english

File:

PDF, 266 KB

english, 2003

19

17β-estradiol inhibits cytokine, chemokine, and chemokine receptor mRNA expression in the central nervous system of female mice with experimental autoimmune encephalomyelitis

Agata Matejuk, Kirsten Adlard, Alex Zamora, Marc Silverman, Arthur A. Vandenbark, Halina Offner

Journal:

Journal of Neuroscience Research

Year:

2001

Language:

english

File:

PDF, 294 KB

english, 2001

20

Diminished frequency of interleukin-10-secreting, T-cell receptor peptide-reactive T cells in multiple sclerosis patients might allow expansion of activated memory T cells bearing the cognate BV gene

Arthur A. Vandenbark, Tom Finn, David Barnes, Nicole Culbertson, Yuan K. Chou, Kevin Hicks, Antony Bakke, Michele Mass, Ruth Whitham, Halina Offner, Dennis Bourdette

Journal:

Journal of Neuroscience Research

Year:

2001

Language:

english

File:

PDF, 196 KB

english, 2001

21

Estrogen treatment induces a novel population of regulatory cells, which suppresses experimental autoimmune encephalomyelitis

Agata Matejuk, Antony C. Bakke, Corwyn Hopke, Jami Dwyer, Arthur A. Vandenbark, Halina Offner

Journal:

Journal of Neuroscience Research

Year:

2004

Language:

english

File:

PDF, 179 KB

english, 2004

22

T-cell hybridoma specific for myelin oligodendrocyte glycoprotein-35–55 peptide produced from HLA-DRB1*1501-transgenic mice

Yuan K. Chou, Nicole Culbertson, Cathleen Rich, Dorian LaTocha, Abigail C. Buenafe, Jianya Huan, Jason Link, J.M. Wands, Willi K. Born, Halina Offner, Dennis N. Bourdette, Gregory G. Burrows, Arthur A

Journal:

Journal of Neuroscience Research

Year:

2004

Language:

english

File:

PDF, 447 KB

english, 2004

23

HLA-DRB1*1501 risk association in multiple sclerosis may not be related to presentation of myelin epitopes

Thomas P. Finn, Richard E. Jones, Cathleen Rich, Rony Dahan, Jason Link, Chella S. David, Yuan K. Chou, Halina Offner, Arthur A. Vandenbark

Journal:

Journal of Neuroscience Research

Year:

2004

Language:

english

File:

PDF, 903 KB

english, 2004

24

Neuroimmunoprotective effects of estrogen and derivatives in experimental autoimmune encephalomyelitis: Therapeutic implications for multiple sclerosis

Journal:

Journal of Neuroscience Research

Year:

2004

Language:

english

File:

PDF, 1.13 MB

english, 2004

25

Decreased FOXP3 levels in multiple sclerosis patients

Jianya Huan, Nicole Culbertson, Leslie Spencer, Richard Bartholomew, Gregory G. Burrows, Yuan K. Chou, Dennis Bourdette, Steven F. Ziegler, Halina Offner, Arthur A. Vandenbark

Journal:

Journal of Neuroscience Research

Year:

2005

Language:

english

File:

PDF, 330 KB

english, 2005

26

Estrogen-mediated immunomodulation involves reduced activation of effector T cells, potentiation of treg cells, and enhanced expression of the PD-1 costimulatory pathway

Magdalena J. Polanczyk, Corwyn Hopke, Arthur A. Vandenbark, Halina Offner

Journal:

Journal of Neuroscience Research

Year:

2006

Language:

english

File:

PDF, 407 KB

english, 2006

27

Down-modulation of programmed death 1 alters regulatory T cells and promotes experimental autoimmune encephalomyelitis

Chunhe Wang, Yuexin Li, Thomas M. Proctor, Arthur A. Vandenbark, Halina Offner

Journal:

Journal of Neuroscience Research

Year:

2010

Language:

english

File:

PDF, 585 KB

english, 2010

28

Transmembrane signalling associated with ganglioside-induced CD4 modulation

William J. Morrison, Halina Offner, Arthur A. Vandenbark

Journal:

Immunopharmacology

Year:

1990

Language:

english

File:

PDF, 569 KB

english, 1990

29

Ganglioside (GM1)-treated T cells shed CD4

William J. Morrison, Halina Offner, Arthur A. Vandenbark

Journal:

Immunopharmacology

Year:

1991

Language:

english

File:

PDF, 605 KB

english, 1991

30

Antigen-specific t-cell activations distinguished by in vivo anti-CD4 antibody treatment

William J. Morrison, Norman J. Kennedy, Halina Offner, Arthur A. Vandenbark

Journal:

International Journal of Immunopharmacology

Year:

1995

Language:

english

File:

PDF, 695 KB

english, 1995

31

Effects of vaccination with T cell receptor peptides: Epitope switching to a possible disease-protective determinant of myelin basic protein that is cross-reactive with a TCR BV peptide

VANDENBARK, ARTHUR A, CHOU, YUAN K, WHITHAM, RUTH, BOURDETTE, DENNIS N, OFFNER, HALINA

Journal:

Immunology & Cell Biology

Year:

1998

Language:

english

File:

PDF, 268 KB

english, 1998

32

Treatments targeting the T cell receptor (TCR): effects of TCR peptide-specific T cells on activation, migration, and encephalitogenicity of myelin basic protein-specific T cells

Halina Offner, Ray Jacobs, Bruce F. Bebo, Arthur A. Vandenbark

Journal:

Seminars in Immunopathology

Year:

1999

Language:

english

File:

PDF, 920 KB

english, 1999

33

CD4+FoxP3+regulatory T-cells in cerebral ischemic stroke

Xuefang Ren, Kozaburo Akiyoshi, Arthur A. Vandenbark, Patricia D. Hurn, Halina Offner

Journal:

Metabolic Brain Disease

Year:

2011

Language:

english

File:

PDF, 180 KB

english, 2011

34

Sustained expression of circulating human alpha-1 antitrypsin reduces inflammation, increases CD4+FoxP3+ Treg cell population and prevents signs of experimental autoimmune encephalomyelitis in mice

Sandhya Subramanian, Galit Shahaf, Eyal Ozeri, Lisa M. Miller, Arthur A. Vandenbark, Eli C. Lewis, Halina Offner

Journal:

Metabolic Brain Disease

Year:

2011

Language:

english

File:

PDF, 418 KB

english, 2011

35

Myelin specific cells infiltrate MCAO lesions and exacerbate stroke severity

Xuefang Ren, Kozaburo Akiyoshi, Marjorie R. Grafe, Arthur A. Vandenbark, Patricia D. Hurn, Paco S. Herson, Halina Offner

Journal:

Metabolic Brain Disease

Year:

2012

Language:

english

File:

PDF, 456 KB

english, 2012

36

Therapy with recombinant T-cell receptor ligand reduces infarct size and infiltrating inflammatory cells in brain after middle cerebral artery occlusion in mice

Suzan Dziennis, Sarah Mader, Kozaburo Akiyoshi, Xuefang Ren, Patricia Ayala, Gregory G. Burrows, Arthur A. Vandenbark, Paco S. Herson, Patricia D. Hurn, Halina A. Offner

Journal:

Metabolic Brain Disease

Year:

2011

Language:

english

File:

PDF, 461 KB

english, 2011

37

Contribution of GPR30 for 1,25 dihydroxyvitamin D3protection in EAE

Sandhya Subramanian, Lisa M. Miller, Marjorie R. Grafe, Arthur A. Vandenbark, Halina Offner

Journal:

Metabolic Brain Disease

Year:

2012

Language:

english

File:

PDF, 534 KB

english, 2012

38

Recombinant T Cell Receptor Ligands Improve Outcome After Experimental Cerebral Ischemia

Kozaburo Akiyoshi, Suzan Dziennis, Julie Palmateer, Xuefang Ren, Arthur A. Vandenbark, Halina Offner, Paco S. Herson, Patricia D. Hurn

Journal:

Translational Stroke Research

Year:

2011

Language:

english

File:

PDF, 200 KB

english, 2011

39

Critical evaluation of regulatory T cells in autoimmunity: are the most potent regulatory specificities being ignored?

Arthur A. Vandenbark, Halina Offner

Journal:

Year:

2008

Language:

english

File:

PDF, 470 KB

english, 2008

40

Oestrogen modulates experimental autoimmune encephalomyelitis and interleukin-17 production via programmed death 1

Chunhe Wang, Babak Dehghani, Yuexin Li, Laurie J. Kaler, Arthur A. Vandenbark, Halina Offner

Journal:

Year:

2009

Language:

english

File:

PDF, 402 KB

english, 2009

41

Prevention and treatment of experimental autoimmune encephalomyelitis with clonotypic CDR3 peptides: CD4+ FoxP3+ T-regulatory cells suppress interleukin-2-dependent expansion of myelin basic protein-specific T cells

Abigail C. Buenafe, Shayne Andrew, Michael Afentoulis, Halina Offner, Arthur A. Vandenbark

Journal:

Year:

2010

Language:

english

File:

PDF, 381 KB

english, 2010

42

Oestrogen-mediated protection of experimental autoimmune encephalomyelitis in the absence of Foxp3+ regulatory T cells implicates compensatory pathways including regulatory B cells

Sandhya Subramanian, Melissa Yates, Arthur A. Vandenbark, Halina Offner

Journal:

Year:

2011

Language:

english

File:

PDF, 646 KB

english, 2011

43

Regulatory T cells play a role in T-cell receptor CDR2 peptide regulation of experimental autoimmune encephalomyelitis

Abigail C. Buenafe, Shayne Andrew, Halina Offner, Arthur A. Vandenbark

Journal:

Year:

2012

Language:

english

File:

PDF, 512 KB

english, 2012

44

Antigen-Specific Therapy Promotes Repair of Myelin and Axonal Damage in Established EAE

Chunhe Wang, Bruce G. Gold, Laurie J. Kaler, Xiaolin Yu, Michael E. Afentoulis, Gregory G. Burrows, Arthur A. Vandenbark, Dennis N. Bourdette, Halina Offner

Journal:

Journal of Neurochemistry

Year:

2006

Language:

english

File:

PDF, 1.31 MB

english, 2006

45

Immunization with a synthetic T-cell receptor V-region peptide protects against experimental autoimmune encephalomyelitis

Vandenbark, Arthur A., Hashim, George, Offner, Halina

Journal:

Year:

1989

File:

PDF, 432 KB

1989

46

Treatment of multiple sclerosis with T–cell receptor peptides: Results of a double–blind pilot trial

Vandenbark, Arthur A., Chou, Yuan K., Whitham, Ruth, Mass, Michele, Buenafe, Abigail, Liefeld, Diane, Kavanagh, Daniel, Cooper, Shelley, Hashim, George A., Offner, Halina

Journal:

Nature Medicine

Year:

1996

File:

PDF, 778 KB

1996

47

Experimental stroke induces massive, rapid activation of the peripheral immune system

Offner, Halina, Subramanian, Sandhya, Parker, Susan M, Afentoulis, Michael E, Vandenbark, Arthur A, Hurn, Patricia D

Journal:

Journal of Cerebral Blood Flow and Metabolism

Year:

2005

Language:

english

File:

PDF, 189 KB

english, 2005

48

T- and B-cell-deficient mice with experimental stroke have reduced lesion size and inflammation

Hurn, Patricia D, Subramanian, Sandhya, Parker, Susan M, Afentoulis, Michael E, Kaler, Laurie J, Vandenbark, Arthur A, Offner, Halina

Journal:

Journal of Cerebral Blood Flow and Metabolism

Year:

2007

Language:

english

File:

PDF, 140 KB

english, 2007

49

A Potential Role for Estrogen in Experimental Autoimmune Encephalomyelitis and Multiple Sclerosis

HALINA OFFNER, MAGDALENA POLANCZYK

Journal:

Annals of the New York Academy of Sciences

Year:

2006

Language:

english

File:

PDF, 1.47 MB

english, 2006

50

TCR Peptide Therapy in Human Autoimmune Diseases

Arthur A. Vandenbark, Elizabeth Morgan, Richard Bartholomew, Dennis Bourdette, Ruth Whitham, Dennis Carlo, Daniel Gold, George Hashim, Halina Offner

Journal:

Neurochemical Research

Year:

2001

Language:

english

File:

PDF, 77 KB

english, 2001

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